Keep your dog protected from fleas, ticks, intestinal worms, and deadly heartworm—all with a single, easy-to-give chew. Simparica TRIO is a once-a-month, liver-flavored tablet that offers broad-spectrum parasite protection in a form your dog will enjoy.
Developed by trusted veterinary experts, Simparica TRIO delivers powerful, lasting defense against the three major threats to canine health—making it one of the most comprehensive parasite treatments available for dogs.
Why Choose Simparica TRIO?
Fast-Acting Flea Control Kills fleas quickly before they lay eggs—preventing infestations and protecting your home
Tick Protection Effectively treats and controls paralysis ticks and brown dog ticks for up to 35 days
Heartworm Prevention Delivers 100% proven protection against deadly heartworm disease
Intestinal Worm Treatment Treats and controls hookworms and roundworms, including infectious larval stages
Controls Flea Allergy Dermatitis Helps relieve itching and skin irritation caused by flea allergies
One Monthly Dose Convenient once-a-month chew with triple-action protection
Total Parasite Protection in One Chew
Whether you're protecting your pup from fleas or guarding against more serious threats like heartworm and ticks, Simparica TRIO makes parasite prevention simple, effective, and stress-free.
Beef-Flavored Chew
Protects dogs against fleas, ticks, heartworms, roundworms, and hookworms in one monthly chewable.
Safe for Puppies
Tasty, liver-flavored chew loved by dogs—easy to administer with or without food.
Breed-Safe Formula
Also effective against five common tick species, including Lone Star and Deer ticks.
Heartworm Prevention
Starts killing fleas within 4 hours and ticks within 8 hours of administration.
Controls Worms
Vet-prescribed for broad-spectrum parasite control in dogs 8 weeks and older.
Convenient Monthly Dose
Offers reliable, month-long protection with a single chew.
Vet-Approved Formulas
Prescription-Grade Quality
Recommended by Veterinarians
Easy Rx Verification
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